Fly ash from a coal burning electric power plant was used to reduce the soil acidity in a Southeast Missouri cotton field. Three rates of fly ash as well as an untreated check were compared. Fly ash treatments raised soil pH levels over a 5-month period. Fly ash rate did not significantly effect cotton lint yields. Boron, potassium, and sodium levels in cotton leaves and petioles collected during full bloom were increased for fly ash treatments. The magnitude of these increases corresponds to the fly ash application rates. Manganese levels in leaf and petiole were reduced for fly ash treatments. Total soil manganese levels were similar for all treatments. DTPA extractable manganese levels were lower for fly ash treatments.