Variety selection is one of the first, and perhaps the single most important, decisions a cotton producer makes each season. This research was intended to be an aid the producers in selecting the best cotton variety to plant. Certain data will also be of interest to ginners, millers, and other sectors of the cotton industry. The varieties reported on in this paper were submitted by the cottonseed companies and are new releases or entries that have not been in the Mississippi Cotton Variety Trials prior to 1999.