As in any crop, managing diseases is important for successful cotton production. Despite the weak market price producers are currently receiving for their cotton, disease management cannot be ignored. Fortunately, there are several practices that producers can use to manage most diseases that add little to production costs. There are also practices that can be used to reduce fungicide or nematicide costs or maximize the benefits of fungicides and nematicides. These practices include crop rotation, planting disease resistant cultivars, and employing other cultural practices such as delaying planting, proper fertility, and insect and irrigation management.