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Mast cells are of central importance to the immediate and chronic effects of lung inflammation typified by bronchial hyperreactivity, through release of inflammatory mediators including histamine. This work examines the histamine releasing effect of Lipopolysaccharide and (1 3)-b-D-glucan, both of which are found in cotton and other organic dusts, on mast cells isolated from the rat peritoneum and guinea pig lung. |
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©National Cotton Council, Memphis TN |
Document last modified Monday, Jun 21 1999
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