A replicated large plot field trial was conducted to examine the effects of selected insecticides on pest and beneficial arthropods in cotton. Insecticides targeted for boll weevil control were aerially applied to plots of approximately 10 acres each on a 5 day schedule for 5 applications. Guthion, Baythroid and Legend (Baythroid plus Provado) were evaluated. Pest densities were low and all three products provided good control of boll weevils. Guthion (in oil) and Legend provided good control of cotton fleahoppers. Although whitefly and aphid densities were low, Legend appeared to reduce the potential for flaring these pests as compared to the pyrethroid alone. Baythroid was less detrimental to the beneficial arthropods present than Guthion. Addition of Provado with Baythroid (Legend) was also more detrimental to some species of beneficial arthropods than Baythroid alone.