Four adaptive program approaches for Bt cotton were compared in small plot trials. Insecticides were applied in response to bollworm, Helicoverpa zea (Cresson), boll weevils, Anthonomus grandis (Boddie) or to boll weevils and tarnished plant bug, Lygus lineolaris (Palisot de Beauvois). Programs were adjusted according to infestation threats and were reflective of local concerns about 1) failures to control bollworms with Bt cottons, 2) square shedding induced by newly hatched larvae of both bollworms and tobacco budworms, Heliothis virescens (F.), and 3) failure to control boll weevils and plant bugs in Bt cotton with synthetic pyrethroid insecticides.