Availability of precision technology and GPS systems has prompted interest in variable rate Pix application to cotton. A 14 acre irrigated cotton field was grid and random sampled for 4 weeks during the bloom period. Variagram analysis indicated that a kriged map based on the spherical model and grid data adequately represents cotton growth in the field. Frequency analysis of percent of field area in a specific range for height, height to node ratio, and average length of top 5 internodes showed a large amount of varibiality in the field. At a uniform Pix rate, the spatial distribution of plant measurements increased over time. Plants in the tallest height range at time of application never adequately responded and were the tallest at final sampling date. Comparison of contour maps generated from the consultants randomly sampled points and the grid points indicated that random sampling did not adequately identify major plant growth zones in the field. Spatial analysis would improve decision process of Pix application. The large amount of variability justifies VRT practices and Pix application.