A regular monitoring of insecticide resistance in Helicoverpa armigera (Hübner) collected from different areas of Pakistan was conducted from 1991 through 1997 using an IRAC leaf-dip method. Generally, a moderate resistance was found to cypermethrin during 1991 to 1993; but it reached to very high levels during 1994 to 1997, following an outbreak of H. armigera on cotton in 1994 when frequent applications of various insecticides were made. Endosulfan resistance was low from 1991 to 1993 and it also became high from 1994 to 1997. Resistance to profenofos and chlorpyrifos remained very low to low levels up to 1995, but rose to moderate levels in 1996 and 1997. However, resistance to thiodicarb was consistently very low throughout the seven-year period. Unless a management strategy is adopted, insecticide resistance in H. armigera and other pests may continue to threaten cotton production in Pakistan.