Much of the recent attention on weed management in cotton as focused on annual broadleaf weed control with the new POST biotechnology options. Despite many advances and new registrations, nutsedge species remain very troublesome and difficult to control. Nutsedge species infest 35% and 58% of cotton grown in North Carolina and Georgia, respectively and reduce net income by an estimated 2.1 to 11.4 million dollars. Studies were conducted in Williamson, GA and Lewiston, NC to evaluate various soil-applied programs with cultivation, with two applications of MSMA PDS + cultivation, and with Staple + MSMA and MSMA PDS + cultivation for nutsedge control over a two year period.