A field study was established near Rohwer, AR in 1997 to evaluate sicklepod [Senna obtusifolia (L.) Irwin and Barneby] control with different Staple (pyrithiobac) weed control programs. Staple was applied preemergence (PRE) at 0.6 or 0.8 oz pr/A as a single application or in combination with Cotoran (fluometuron) at 1.9 or 2.5 pt pr/A. Single postemergence (POST) applications of Staple at 0.6 or 1 oz/A or tank-mixed with MSMA (monosodium methanearsonate) at 1.0 pt pr/A were applied to 3 leaf cotton. The entire test area received Prowl (pendimethalin) at 2.3 pt pr/A PRE.