Conventional caustic and enzymatic scouring, solvent extraction, mercerization and cellulase enzyme treatments were performed on Coyote, Buffalo (brown varieties) and Green naturally pigmented cotton yarns. The effect of these wet treatments on the color shade was evaluated using the CIEL*a*b* color system. It was found that caustic treatments had the highest impact on the hue of these fibers. Further, Coyote and Buffalo plain weave fabrics were treated with metal salt solutions. A dramatic color shift towards darker browns and gray-browns was observed with solutions containing Fe(II) ions while other cations proved to be less effective.