Information on phosphorus (P2O5) and potassium (K2O) nutrition for no-tillage (NT) cotton (Gossypium hirsutum L.) production is limited. Research was initiated in 1994 and continued through 1997 on a Loring silt loam at the Milan Experiment Station evaluating P2O5 and K2O fertilization rates for conventional- (CT) and NT production systems. Mehlich I extractable P was low and extractable K was medium. The experimental design was a split plot. Main plots were tillage with P2O5- K2O rates sub-plots. The P2O5 rates were 0, 40, 80, and 120 lb/acre while the K2O rates were 0, 30, and 60 lb/acre. Treatments were replicated four times. Research was initiated in 1995 and continued in 1997 on a Lexington silt loam at the West Tennessee Experiment Station, a Loring silt loam at the Milan Experiment Station and on a Memphis silt loam at Ames Plantation evaluating K2O fertilization of NT cotton. Mehlich I extractable K was high, high, and low for the three soils respectively. The experimental design for the K tests was a RCB with treatments replicated five times. K2O rates of 0, 30, 60, 90, 120, 150, and 180 lb/acre were surface applied at each location. All experiments were fertilized with 80 lb N/acre after planting. D&PL 50 was planted 1995 and 1996 with D&PL 5409 planted in 1997. Experiments were planted in May.