The purpose of this study was to determine the effect of temperature on the drying rates of gin run cotton seed and to develop generalized relationships for drying cotton seed. Data showing moisture absorption and desorption rates for gin run cotton seed were collected. Absorption data was obtained for temperatures of 68 and 95°F and desorption values for temperatures ranging from 68 to 266°F. Generalized solutions were developed for the theoretical falling rate equation from the experimental data for the drying (desorption) data. The falling rate (exponential decay) function fit the data reasonably well, especially at temperatures above 212°F. The generalized solution of the falling rate equation was developed as a function of absolute temperature (°R), which should be suitable for engineering calculations. Results indicate that moisture absorption by cotton seed undergoes two absorption phases. The first absorption phase appears to be physical in nature and approximates the curves of other biological materials. The second phase, which shows an increased moisture absorption rate after a leveling off period, may indicate increased metabolic activity.