Vegetative and Reproductive growth of cotton (Gossypium hirsutum) was monitored in a seven cultivar by three plant growth regulator (PGRs) study over two years. The study was designed as a split-plot with the PGR treatments being the whole plots and the cultivars as sub-plots. Variety yields were erratic in the two years, but PGR yields averaged over varieties were quite consistent. The treatment showing increased yields, boll counts, and reproductive nodes was a mixture of foliar fertilizers applied throughout the season. This treatment increased boll counts at the first three positions on the first ten reproductive branches. This treatment, however, caused an increase in height compared to other PGR treatments receiving mepiquat chloride. Increased plant height may lead to a delay in maturity. Another study was conducted with MFX experimental compounds in 1996 only. This study showed that all MFX compounds had heights similar to mepiquat chloride. MFX-4294 and MFX 2294 at 8 oz/A had more reproductive nodes than the mepiquat chloride treatment. These nodes were produced prior to plant cutout, when boll production was at a maximum. A trend was also noted that these two compounds had more bolls at fruiting positions 1 through 3 than the mepiquat chloride treatment. These new MFX compound may help to produce a shorter plant that matures more quickly and does not sacrifice boll production.