TEMIK® Brand Pesticide is widely used across the cotton belt as an at-planting treatment for early season insect and nematode control. However, sidedress applications have not been widely used in the Mid-South. Owing to varietal changes, the discovery of tarnished plant bug, Lygus lineolaris, resistance (13, 14, 15, 16) and increased nematode yield losses (2), we theorized that sidedress applications of TEMIK® could protect plants during a period of vulnerability between square initiation and bloom. Therefore, the effects of TEMIK® as sidedress applications at varying rates in nematode- and non-nematode- infested soils were compared to standard at-planting treatments of TEMIK® at two locations. One trial was conducted at Minter City, MS. on SureGrow 125 in soil infested by root-knot, Meloidogyne incognita, and reniform, Rotylenchus reniformis, nematodes. The other trial was conducted at Memphis, TN. on Nu-Cotn 33B in non-nematode- infested soils. Results from box mapping data showed the greatest response to sidedress applications in nematode- infested soils but both locations indicated increased first position boll retention and yield between nodes 9-14.