ABSTRACT
A mutation of the common Notch gene acts as a temperature dependent lethal during development when exposed to temperatures below 20o C during embryogenesis. The mutant gene is dominant and a single copy expresses the lethal phenotype in the presence of two copies of the normal Notch gene. Transformation strategies are being used to construct pink bollworm strains that contain copies of the mutant Notch gene. These strategies employ the newly discovered transposable elements, Hobo, Hermes and PiggyBac.
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