Interest and use of Bacillus thuringiensis (Bt) formulations to control cotton insect pests has declined recently primarily due to the success of transgenic cotton expressing the Cry1Ac gene (Bt cotton) to control the tobacco budworm, Heliothis virescens. However, Bt cotton is less efficacious against other pests such as cotton bollworm, Helicoverpa zea, beet armyworm, Spodoptera exigua, and the fall armyworm, S. frugiperda. Additionally, widespread concern over the threat of insecticide resistance developing against these single Bt toxin plants allows for reconsideration of the positive attributes of current and future Bt formulated materials. This presentation will re-visit the positive attributes of Bt formulated products and discuss the more recent discoveries in Bt research which may allow for Bt formulations to fill an important role in cotton insect control.