Herbicide combinations are a routine part of weed control in many field crops and are heavily used in cotton. Combinations such as PRE-POST sequentials, POST-POST sequentials, tank mixes and package mixes are used to obtain multiple benefits and to offset strengths and weaknesses. Some strenths of Staple (pyrithiobac sodium) include pigweed, morningglory and residual control. Some weaknesses of Staple include large cocklebur and grasses. Conversely, Buctril (bromoxynil) is strong on large cockleubr, but weak on pigweed and Buctril has no residual activity. Roundup (glyphosate) is strong on large cocklebur and grasses, but can be weak on morningglory and Roundup has no residual activity. Consequently Staple-Buctril and Staple-Roundup combinations (in thier respecive herbicide-tolearnt crops) would appear to be complementary mixes. These types of combinations were evaluated on a limited scale in 1995 and 1996.