South Carolina, North Carolina, and Virginia cotton growers were surveyed in the fall of 1996 to determine their perception of Staple's performance during its first year of commercialization. Staple was used banded as well as broadcast treatment. The majority of growers in SC and NC used Staple as a replacement treatment as opposed to an additional treatment in their weed control program. Some growers tank-mixed Staple with another herbicide; most commonly MSMA or DSMA. In SC, the top five weeds targeted were Palmer amaranth (Amaranthus palmeri), morningglory species (Ipomoea spp.), sicklepod (Senna obtusifolia), common cocklebur (Xanthium strumarium), and nutsedge species (Cyperus spp.). In NC, the top five weeds targeted were pigweed species (Amaranthus spp.) morningglory species, common cocklebur, sicklepod, and smartweed species (Polygonum spp.). In VA, the top five weeds targeted were cocklebur, jimsonweed (Datura stramonium), morningglory species, pigweed species, and nutsedge species. In SC, growers reported acceptable control of Palmer amaranth, morningglory species, and common cocklebur. In contrast, SC growers reported unacceptable control of sicklepod and nutsedge species. In NC, growers reported acceptable control of morningglory species, pigweed species, and common cocklebur, while reporting unacceptable control of sicklepod and nutsedge species. In VA, growers reported acceptable control of jimsonweed, cocklebur, morningglory species, pigweed species, and nutsedge species. Growers in SC, NC, and VA reported fair to good control of smartweed species. Some cotton injury following application of Staple was observed in VA, SC, and NC; however, few growers felt the injury was not in an acceptable range. In SC and NC, no grower observed differences in tolerance to Staple using the cotton varieties planted. In VA, one grower felt that DP 20 was more susceptible to Staple injury. The majority of the growers who responded felt Staple was a cost-effective addition to their cotton weed management programs.