This research represents the first attempt to identify the economically feasible transportation distance for feedlot manure utilization in the Texas High Plains (THP). This analysis incorporates the residual benefits from manure and in addition provides information related to soil types, and cropping activities predominant in the THP. In many cases, the results suggest that feedlot manure utilization produces favorable yield responses for cotton (both irrigated and dryland) and appears to be a viable alternative to commercial fertilizer.