In-furrow applied fungicides were evaluated at their lowest recommended rate and at reduced rates alone or in combination with hopper-box fungicides for the control of cotton seedling diseases. Plots were inoculated to increase disease pressure. In general, the lowest recommended rate and three-forths for granular in-furrow formulations and one-half for liquid formulation preformed comparably. Addition of a hopper-box treatment was additative and increased fungicide efficacy with granular formulations but not with liquid formations. In-furrow fungicides were the most efficious when disease pressure was high. The liquid formulations preformed slightly better than the granular formulations when the same amount of active ingredient was applied.