Processing factors, such as time of harvest, number of lint cleaners used at the gin, opening line cleaning in the mill, single and tandem carding, combing and rewiring of the card are studied to see the effect on white specks in the finished fabrics. This paper examines the white speck phenomena as seen in four different studies. The first study compares single carding with tandem carding. Tandem carding is shown to increase the white speck problem although it improves all other yarn and fabric qualities. The second study looks at a Midsouth cotton harvested at three different intervals (early harvest, normal harvest, and late harvest). Each of the harvested cottons have three levels of cleaning at the gin and three levels of cleaning in the mill opening line, producing nine different cleaning sequences for each harvest. The results identify the optimum balance between lint cleaning at the gin versus cleaning at the mill as related to white specks. The third study compares carding with combing. Four varieties from the 26 Leading Variety Study by AMS were carded and combed and the fabrics are analyzed for white specks. The final study compares new card wire with used card. The card wire was damaged in the middle of a study, the card was rewired, the bale samples were processed again on the new wires and the results are presented here. Both combing and rewiring are found to reduced the white speck problem, while other processing seems to open and separate the immature fibers spreading the white speck problem.