The yield performance and yield stability of six cotton experimental lines and three cotton cultivars were evaluated on eight environments of the Comarca Lagunera, México. Eberhart and Russell stability parameters were used to measure the genotypes yield stability. The combined analysis of variance showed significant differences in the mean lint yield of the genotypes, but there were not significant genotype x environment interaction. According to the genotypes yielding potential and the stability indexes, the most desirable genotypes were the experimental lines, D. 2782-3 and D. 2784-1, and the cultivar Laguna 89.