The response of two infrared moisture meters to cotton density was determined in this study. An adjustable, mechanical device to aid in maintaining a given level of cotton density for viewing by an infrared meter and a positioning device to maintain the sample cotton at a constant distance were constructed. Density levels for seed cotton and lint of 0.05 to 0.25 g/cm³ were used in the study. For the QBII meter, moisture and density as well as their interaction were significant for measurements on lint. For the QBII meter measurements on seed cotton, only the moisture and density effects were significant. For the QA60 meter which had an additional filter at a different wavelength, only moisture levels were significant. The additional filter added to the QA60 meter eliminated some of the measurement affects of density.