Evaluation of potential carry over of herbicides is critical in both product development by industry and in farmer decisions concerning rotational schemes. Experiments were conducted to evaluate the potential carryover of KIH-8921 (DPX-PE350, chemistry not released) on various crops planted after cotton (Gossypium hirsutum L.). Residues of KIH-8921 injured grain sorghum [Sorghum bicolor (L.) Moench] on a Sharkey silty clay approximately one year after application. Maturity also was delayed; however, there was no reduction in grain yield. On a silt loam soil, there was no evidence of persistence one year after application on rice (Oryza sativa L.), soybeans (Glycine max L.), grain sorghum, corn (Zea mays L.), or peanuts (Arachis hypogea L.).