With the increased cost of labor, weed control through the use of transgenic crops has been of particular interest to growers in Texas. Therefore, seven experiments were established in the High Plains, Rolling Plains, and Central Texas to evaluate various herbicide programs using both the Roundup Ready and BXN technology. The first two experiments evaluated the use of a dinitroaniline and cultivation with Roundup Ultra (glyphosate) for control of morningglory species (Ipomoea sp.) and Palmer amaranth (Amaranthus palmeri). The third experiment evaluated Roundup Ultra application timings for control of silverleaf nightshade (Solanum elaeagnifolium), a tough to control perennial weed problem in Texas cotton. The fourth study evaluated the use of Staple (pyrithiobac) in combination with Roundup Ultra for control of purple nutsedge (Cyperus rotundus). The fifth study evaluated various residual herbicide programs with Buctril (bromoxynil) for control of common cocklebur (Xanthium strumarium). The final two studies evaluated the use of Staple in combination with Buctril for control of morningglory (Ipomoea sp.) and pigweed (Amaranthus sp.) species.